Mathematical Modeling in Biology REU

I’m one of of the faculty mentors for the Mathematical Modeling in Biology REU program, which I originally talked about here. Two of our five students are working with me on a project this summer. We are a three-woman dream team!

We are studying mathematical models of how organisms coexist and compete while using the same resources in an ecosystem. There are a variety of ways that organisms use resources. For example, plants need nitrate and phosphate to grow, and without sufficient quantities of both of these nutrients, the plant will die. On the other hand, humans can get energy for daily activities from carbohydrates, protein or fats. If we don’t have carbohydrates, we can substitute some protein or fat and get by; for the sake of providing us with energy, we need any one of these, but we don’t need all. Modeling has been used with multiple organisms using one type of nutrient utilization, but not a lot with multiple organisms having multiple ways of utilizing nutrients. That’s what we are working on.

Mathematical Modeling in Biology REU Group

Mathematical Modeling in Biology REU Group

Thus far, we’ve reproduced some results from existing models with a common type of nutrient utilization; in particular, we’ve shown how one organism can outcompete others for the same resources, and how two organisms can coexist even though they both utilize the same resources. We are working on learning some of the background science of how organisms use resources and the equations and mathematics associated with this. We are performing a literature review to familiarize ourselves with what research has been done in the past and has been published recently. We are learning what types of questions scientists are interested in and have answered in the past, and also figuring out where we can make a novel contribution. And, given that we are a mathematics program, it won’t surprise you to learn that we are developing the equations we need to make the modifications required to the model we have so that we can do something new.

The other three students in our program have interesting problems to work on as well. Two are working on mathematical models for how atherosclerosis (hardening of the arteries) occurs and how diet and exercise might improve arterial health. One student is working on mathematical models for controlling invasive species; personally, I am hoping he will find a way to mitigate the spread of fireants.

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